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Histone Deacetylase Inhibition Impairs Normal Intestinal Cell Proliferation and Promotes Specific Gene Expression

Mechanisms that maintain proliferation and delay cell differentiation in the intestinal crypt are not yet fully understood. We have previously shown the implication of histone methylation in the regulation of enterocytic differentiation. In this study, we investigated the role of histone deacetylati...

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Detalles Bibliográficos
Autores principales: Roostaee, Alireza, Guezguez, Amel, Beauséjour, Marco, Simoneau, Aline, Vachon, Pierre H., Levy, Emile, Beaulieu, Jean‐François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014201/
https://www.ncbi.nlm.nih.gov/pubmed/26129821
http://dx.doi.org/10.1002/jcb.25274

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