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Conserved patterns hidden within group A Streptococcus M protein hypervariability are responsible for recognition of human C4b-binding protein
No vaccine exists against group A Streptococcus (GAS), a leading cause of worldwide morbidity and mortality. A severe hurdle is the hypervariability of its major antigen, the M protein, with >200 different M types known. Neutralizing antibodies typically recognize M protein hypervariable regions...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014329/ https://www.ncbi.nlm.nih.gov/pubmed/27595425 http://dx.doi.org/10.1038/nmicrobiol.2016.155 |