A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA

Hepatitis B virus (HBV) infection is a major cause of chronic active hepatitis, cirrhosis, and primary hepatocellular carcinoma, all of which are severe threats to human health. However, current clinical therapies for HBV are limited by potential side effects, toxicity, and drug-resistance. In this...

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Detalles Bibliográficos
Autores principales: Zeng, Zhengyang, Han, Shisong, Hong, Wei, Lang, Yange, Li, Fangfang, Liu, Yongxiang, Li, Zeyong, Wu, Yingliang, Li, Wenxin, Zhang, Xianzheng, Cao, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014453/
https://www.ncbi.nlm.nih.gov/pubmed/26978579
http://dx.doi.org/10.1038/mtna.2016.11

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