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In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats

Bone remodeling requires a precise balance between formation and resorption. This complex process involves numerous factors that orchestrate a multitude of biochemical events. Among these factors are hormones, growth factors, vitamins, cytokines, and, most notably, osteoprotegerin (OPG) and the rece...

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Detalles Bibliográficos
Autores principales: Hoffmann, Daniel B, Böker, Kai O, Schneider, Stefan, Eckermann-Felkl, Ellen, Schuder, Angelina, Komrakova, Marina, Sehmisch, Stephan, Gruber, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014456/
https://www.ncbi.nlm.nih.gov/pubmed/27003757
http://dx.doi.org/10.1038/mtna.2016.15