Cargando…
CodonShuffle: a tool for generating and analyzing synonymously mutated sequences
Because synonymous mutations do not change the amino acid sequence of a protein, they are generally considered to be selectively neutral. Empiric data suggest, however, that a significant fraction of viral mutational fitness effects may be attributable to synonymous mutation. Bias in synonymous codo...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014483/ https://www.ncbi.nlm.nih.gov/pubmed/27774284 http://dx.doi.org/10.1093/ve/vev012 |