Development of Lentiviral Vectors Simultaneously Expressing Multiple siRNAs Against CCR5, vif and tat/rev Genes for an HIV-1 Gene Therapy Approach

Gene therapy holds considerable promise for the functional cure of HIV-1 infection and, in this context, RNA interference (RNAi)-based approaches represent powerful strategies. Stable expression of small interfering RNAs (siRNAs) targeting HIV genes or cellular cofactors has the potential to render...

Descripción completa

Detalles Bibliográficos
Autores principales: Spanevello, Francesca, Calistri, Arianna, Del Vecchio, Claudia, Mantelli, Barbara, Frasson, Chiara, Basso, Giuseppe, Palù, Giorgio, Cavazzana, Marina, Parolin, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014525/
https://www.ncbi.nlm.nih.gov/pubmed/27093170
http://dx.doi.org/10.1038/mtna.2016.24

Ejemplares similares

Ejemplares similares