Hemagglutinin-targeting Artificial MicroRNAs Expressed by Adenovirus Protect Mice From Different Clades of H5N1 Infection

Influenza virus (IV) is a continuously evolving virus that widely spreads in humans and contributes to substantial morbidity and mortality. Re-emergence of human infection with avian influenza virus H5N1 poses extra challenge to IV control. Artificial microRNA (amiRNA)-mediated RNA interference has...

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Detalles Bibliográficos
Autores principales: Tang, Xinying, Zhang, Hongbo, Song, Yufeng, Zhou, Dongming, Wang, Jieru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014526/
https://www.ncbi.nlm.nih.gov/pubmed/27093169
http://dx.doi.org/10.1038/mtna.2016.25

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