The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis

Synovial sarcomas are aggressive soft-tissue malignancies that express chromosomal translocation-generated fusion genes, SS18-SSX1 or SS18-SSX2 in most cases. Here, we report a mouse sarcoma model expressing SS18-SSX1, complementing our prior model expressing SS18-SSX2. Exome sequencing identified n...

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Detalles Bibliográficos
Autores principales: Jones, Kevin B., Barrott, Jared J., Xie, Mingchao, Haldar, Malay, Jin, Huifeng, Zhu, Ju-Fen, Monument, Michael J., Mosbruger, Tim L., Langer, Ellen M., Randall, R. Lor, Wilson, Richard K., Cairns, Bradley R., Ding, Li, Capecchi, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014712/
https://www.ncbi.nlm.nih.gov/pubmed/26947017
http://dx.doi.org/10.1038/onc.2016.38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014712/
https://www.ncbi.nlm.nih.gov/pubmed/26947017
http://dx.doi.org/10.1038/onc.2016.38

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