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The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis

Synovial sarcomas are aggressive soft-tissue malignancies that express chromosomal translocation-generated fusion genes, SS18-SSX1 or SS18-SSX2 in most cases. Here, we report a mouse sarcoma model expressing SS18-SSX1, complementing our prior model expressing SS18-SSX2. Exome sequencing identified n...

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Detalles Bibliográficos
Autores principales:	Jones, Kevin B., Barrott, Jared J., Xie, Mingchao, Haldar, Malay, Jin, Huifeng, Zhu, Ju-Fen, Monument, Michael J., Mosbruger, Tim L., Langer, Ellen M., Randall, R. Lor, Wilson, Richard K., Cairns, Bradley R., Ding, Li, Capecchi, Mario R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014712/ https://www.ncbi.nlm.nih.gov/pubmed/26947017 http://dx.doi.org/10.1038/onc.2016.38

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