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MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

Through an RNAi-based screen for previously uncharacterized regulators of genome stability, we have identified the human protein C5orf45 as an important factor in preventing the accumulation of DNA damage in human cells. Here, we functionally characterize C5orf45 as a binding partner of the MRE11-RA...

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Detalles Bibliográficos
Autores principales:	Staples, Christopher J., Barone, Giancarlo, Myers, Katie N., Ganesh, Anil, Gibbs-Seymour, Ian, Patil, Abhijit A., Beveridge, Ryan D., Daye, Caroline, Beniston, Richard, Maslen, Sarah, Ahel, Ivan, Skehel, J. Mark, Collis, Spencer J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014761/ https://www.ncbi.nlm.nih.gov/pubmed/27568553 http://dx.doi.org/10.1016/j.celrep.2016.07.087

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