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Venous angioma may be associated with epilepsy in children

PURPOSE: Venous angioma (VA) is the most common congenital abnormality of the intracranial vasculature. This study aimed to investigate the relationship between VA and epilepsy and to identify the characteristics of children with VA and epilepsy. METHODS: The records of all patients aged less than 1...

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Autores principales: Kim, Bo Ryung, Lee, Yun Jin, Nam, Sang Ook, Park, Kyung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pediatric Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014914/
https://www.ncbi.nlm.nih.gov/pubmed/27610183
http://dx.doi.org/10.3345/kjp.2016.59.8.341
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author Kim, Bo Ryung
Lee, Yun Jin
Nam, Sang Ook
Park, Kyung Hee
author_facet Kim, Bo Ryung
Lee, Yun Jin
Nam, Sang Ook
Park, Kyung Hee
author_sort Kim, Bo Ryung
collection PubMed
description PURPOSE: Venous angioma (VA) is the most common congenital abnormality of the intracranial vasculature. This study aimed to investigate the relationship between VA and epilepsy and to identify the characteristics of children with VA and epilepsy. METHODS: The records of all patients aged less than 18 years who underwent brain magnetic resonance imaging (MRI) at Pusan National University Hospital were retrospectively reviewed. Patients with isolated VA and patients with normal MRI were compared in terms of the prevalence of epilepsy. RESULTS: In total, 2,385 pediatric patients who underwent brain MRI were enrolled. Isolated VA was identified in 26 patients (VA group). Among the patients with normal MRI findings, 225 age- and sex-matched patients to the VA-group were assigned to the control group. Nine patients in the VA group (9 of 26, 34.6%) and 27 patients in the control group (26 of 225, 11.5%; P<0.001) had epilepsy. In the VA group, 20 patients (76.9%) had the VA in the cerebral hemispheres, and 6 patients (23.1%) had the VA in the brainstem and cerebellum. The latter showed a higher prevalence of epilepsy (5 of 6, 83.3%) than the former (4 of 20, 20.0%; P=0.004). Among the nine patients who had epilepsy with VA, patients whose VA involved the brainstem and cerebellum showed a significantly higher frequency of abnormal Electroencephalographic findings than patients whose VA involved the cerebral hemispheres (P=0.016). CONCLUSION: VA, especially in the brainstem and cerebellum, might be associated with epilepsy.
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spelling pubmed-50149142016-09-08 Venous angioma may be associated with epilepsy in children Kim, Bo Ryung Lee, Yun Jin Nam, Sang Ook Park, Kyung Hee Korean J Pediatr Original Article PURPOSE: Venous angioma (VA) is the most common congenital abnormality of the intracranial vasculature. This study aimed to investigate the relationship between VA and epilepsy and to identify the characteristics of children with VA and epilepsy. METHODS: The records of all patients aged less than 18 years who underwent brain magnetic resonance imaging (MRI) at Pusan National University Hospital were retrospectively reviewed. Patients with isolated VA and patients with normal MRI were compared in terms of the prevalence of epilepsy. RESULTS: In total, 2,385 pediatric patients who underwent brain MRI were enrolled. Isolated VA was identified in 26 patients (VA group). Among the patients with normal MRI findings, 225 age- and sex-matched patients to the VA-group were assigned to the control group. Nine patients in the VA group (9 of 26, 34.6%) and 27 patients in the control group (26 of 225, 11.5%; P<0.001) had epilepsy. In the VA group, 20 patients (76.9%) had the VA in the cerebral hemispheres, and 6 patients (23.1%) had the VA in the brainstem and cerebellum. The latter showed a higher prevalence of epilepsy (5 of 6, 83.3%) than the former (4 of 20, 20.0%; P=0.004). Among the nine patients who had epilepsy with VA, patients whose VA involved the brainstem and cerebellum showed a significantly higher frequency of abnormal Electroencephalographic findings than patients whose VA involved the cerebral hemispheres (P=0.016). CONCLUSION: VA, especially in the brainstem and cerebellum, might be associated with epilepsy. The Korean Pediatric Society 2016-08 2016-08-24 /pmc/articles/PMC5014914/ /pubmed/27610183 http://dx.doi.org/10.3345/kjp.2016.59.8.341 Text en Copyright © 2016 by The Korean Pediatric Society http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Bo Ryung
Lee, Yun Jin
Nam, Sang Ook
Park, Kyung Hee
Venous angioma may be associated with epilepsy in children
title Venous angioma may be associated with epilepsy in children
title_full Venous angioma may be associated with epilepsy in children
title_fullStr Venous angioma may be associated with epilepsy in children
title_full_unstemmed Venous angioma may be associated with epilepsy in children
title_short Venous angioma may be associated with epilepsy in children
title_sort venous angioma may be associated with epilepsy in children
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014914/
https://www.ncbi.nlm.nih.gov/pubmed/27610183
http://dx.doi.org/10.3345/kjp.2016.59.8.341
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