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Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models

Over the past years, a wide variety of in vivo mouse models have been generated in order to unravel the molecular pathology of Chronic Myeloid Leukemia (CML) and to develop and improve therapeutic approaches. These models range from (conditional) transgenic models, knock-in models, and murine bone m...

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Detalles Bibliográficos
Autores principales: Sontakke, Pallavi, Jaques, Jenny, Vellenga, Edo, Schuringa, Jan Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014953/
https://www.ncbi.nlm.nih.gov/pubmed/27642303
http://dx.doi.org/10.1155/2016/1625015