Cargando…

The Improvement of Hyperglycemia after RYGB Surgery in Diabetic Rats Is Related to Elevated Hypothalamus GLP-1 Receptor Expression

Objectives. This study aimed to explore the expression of GLP-1 receptor in hypothalamus and gastrointestinal tissues after Roux-en-Y gastric bypass (RYGB) surgery in diabetic rats. Methods. Male 12-week-old Wistar rats (control) and Goto-Kakizaki rats (diabetic) were randomly divided into two group...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zynat, Jazyra, Guo, Yuyu, Lu, Yingli, Lin, Dongping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014957/ https://www.ncbi.nlm.nih.gov/pubmed/27648071 http://dx.doi.org/10.1155/2016/5308347

Ejemplares similares

Resistance Exercise Training Attenuates the Loss of Endogenous GLP-1 Receptor in the Hypothalamus of Type 2 Diabetic Rats
por: Park, Se Hwan, et al.
Publicado: (2019)

Differential effects of RYGB surgery and best medical treatment for obesity-diabetes on intestinal and islet adaptations in obese-diabetic ZDSD rats
por: Sridhar, Ananyaa, et al.
Publicado: (2022)

Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice
por: Boland, Brandon B., et al.
Publicado: (2019)

RYGB surgery has modest effects on intestinal morphology and gut hormone populations in the bypassed biliopancreatic limb but causes reciprocal changes in GLP-2 and PYY in the alimentary limb
por: Sridhar, Ananyaa, et al.
Publicado: (2023)

Can reversal of RYGB also reverse hypoglycemia?
por: Arora, Ipsa, et al.
Publicado: (2018)

Wolfram syndrome type 1: a case series
por: Du, Danyang, et al.
Publicado: (2023)

ERCP in RYGB-patients: One size fits all?
por: Aabakken, Lars
Publicado: (2020)

Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus
por: Biddinger, Jessica E, et al.
Publicado: (2020)

Hyperglycemia Induces the Variations of 11β-Hydroxysteroid Dehydrogenase Type 1 and Peroxisome Proliferator-Activated Receptor-γ Expression in Hippocampus and Hypothalamus of Diabetic Rats
por: Qi, Wen-wen, et al.
Publicado: (2012)

Changes in Circulating Cytokines and Adipokines After RYGB in Patients with and without Type 2 Diabetes
por: Katsogiannos, Petros, et al.
Publicado: (2021)

Impact of Abdominal Obesity on Thyroid Auto-Antibody Positivity: Abdominal Obesity Can Enhance the Risk of Thyroid Autoimmunity in Men
por: Zynat, Jazyra, et al.
Publicado: (2020)

Portal Venous Metabolite Profiling After RYGB in Male Rats Highlights Changes in Gut-Liver Axis
por: Stefater, Margaret A, et al.
Publicado: (2020)

Low Serum Vitamin D Is Associated with Anti-Thyroid-Globulin Antibody in Female Individuals
por: Wang, Xinling, et al.
Publicado: (2015)

Gastric Inhibitory Polypeptide (GIP) Is Selectively Decreased in the Roux-Limb of Dietary Obese Mice after RYGB Surgery
por: Zhou, Jiaqiang, et al.
Publicado: (2015)

Improved Insulin Sensitivity 3 Months After RYGB Surgery Is Associated With Increased Subcutaneous Adipose Tissue AMPK Activity and Decreased Oxidative Stress
por: Xu, X. Julia, et al.
Publicado: (2015)

Mechanisms underlying the weight loss effects of RYGB and SG: similar, yet different
por: Pucci, A., et al.
Publicado: (2018)

Purslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes
por: Heidarzadeh, Sara, et al.
Publicado: (2013)

Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A
por: Rajan, Sindhu, et al.
Publicado: (2015)

Repurposed Analog of GLP-1 Ameliorates Hyperglycemia in Type 1 Diabetic Mice Through Pancreatic Cell Reprogramming
por: Villalba, Adrian, et al.
Publicado: (2020)

ODP171 Choosing GLP-1RA Over Insulin for Patients with Type 2 Diabetes and Severe Hyperglycemia
por: Mamtani, Raashi, et al.
Publicado: (2022)

Diagnosis of Gastric Cancer in the Excluded Stomach After RYGB by Jejunogastrostomy Using a LAMS
por: Schneider, Luca, et al.
Publicado: (2021)

Proteomic profiling of the rat hypothalamus
por: Pedroso, Amanda P, et al.
Publicado: (2012)

Management of Hyperglycemia and Diabetes in Orthopedic Surgery
por: Akiboye, Funke, et al.
Publicado: (2017)

The GLP-1 Analogue Exenatide Improves Hepatic and Muscle Insulin Sensitivity in Diabetic Rats: Tracer Studies in the Basal State and during Hyperinsulinemic-Euglycemic Clamp
por: Wu, Hui, et al.
Publicado: (2014)

Vitamin C further improves the protective effect of GLP-1 on the ischemia-reperfusion-like effect induced by hyperglycemia post-hypoglycemia in type 1 diabetes
por: Ceriello, Antonio, et al.
Publicado: (2013)

The Interplay of Adipokines, Body Composition and Glucose Homeostasis in Pregnant Women with a History of RYGB Operation
por: Bellach, Luise, et al.
Publicado: (2023)

Blockade of Central GLP-1 Receptors Deteriorates the Improvement of Diabetes after Ileal Transposition
por: Chen, Weijie, et al.
Publicado: (2016)

Posterior hypothalamus-sparing surgery improves outcome after childhood craniopharyngioma
por: Bogusz, Agnieszka, et al.
Publicado: (2019)

Elevated Midtrimester Triglycerides as a Biomarker for Postpartum Hyperglycemia in Gestational Diabetes
por: Lai, Mengyu, et al.
Publicado: (2020)

The role of pancreas to improve hyperglycemia in STZ-induced diabetic rats by thiamine disulfide
por: Rad, Mahtab Ghanbari, et al.
Publicado: (2022)

GLP-1 reduces metalloproteinase-9 induced by both hyperglycemia and hypoglycemia in type 1 diabetes. The possible role of oxidative stress
por: Ceriello, Antonio, et al.
Publicado: (2015)

Pancreatic alpha cells in diabetic rats express active GLP-1 receptor: Endosomal co-localization of GLP-1/GLP-1R complex functioning through intra-islet paracrine mechanism
por: Nakashima, Koji, et al.
Publicado: (2018)

Stereotaxic surgery for implantation of guide cannulas for microinjection into the dorsomedial hypothalamus in young rats
por: Poole, Emily I., et al.
Publicado: (2019)

Basal-Supported Oral Therapy with Sitagliptin Counteracts Rebound Hyperglycemia Caused by GLP-1 Tachyphylaxis
por: Meguro, Shu, et al.
Publicado: (2014)

Randomized Trial Reveals that Physical Activity and Energy Expenditure are associated with Weight and Body Composition after RYGB
por: Carnero, Elvis Alvarez, et al.
Publicado: (2017)

Betatrophin is downregulated in pregnant women with a history of RYGB operation and a high risk of postprandial hypoglycaemia
por: Leutner, Michael, et al.
Publicado: (2020)

RYGB increases postprandial gastric nesfatin-1 and rapid relieves NAFLD via gastric nerve detachment
por: Wang, Geng, et al.
Publicado: (2020)

Internal Herniation Incidence After RYGB and the Predictive Ability of a CT Scan as a Diagnostic Tool
por: Torensma, Bart, et al.
Publicado: (2020)

Surgical Management of Failed Roux-en-Y Gastric Bypass (RYGB) Reversal: A Case Study
por: Kim, Angie S, et al.
Publicado: (2023)

Roux-En-Y Gastric Bypass (RYGB) Surgery during High Liquid Sucrose Diet Leads to Gut Microbiota-Related Systematic Alterations
por: Zizmare, Laimdota, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_k18j6c5945d1buip2ihvaeere1