Cargando…
Therapeutically targeting mitochondrial redox signalling alleviates endothelial dysfunction in preeclampsia
Aberrant placentation generating placental oxidative stress is proposed to play a critical role in the pathophysiology of preeclampsia. Unfortunately, therapeutic trials of antioxidants have been uniformly disappointing. There is provisional evidence implicating mitochondrial dysfunction as a source...
Autores principales: | McCarthy, Cathal, Kenny, Louise C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015016/ https://www.ncbi.nlm.nih.gov/pubmed/27604418 http://dx.doi.org/10.1038/srep32683 |
Ejemplares similares
-
Activation of a TLR9 mediated innate immune response in preeclampsia
por: Williamson, Rachel D., et al.
Publicado: (2019) -
Placental Ageing in Adverse Pregnancy Outcomes: Telomere Shortening, Cell Senescence, and Mitochondrial Dysfunction
por: Manna, Samprikta, et al.
Publicado: (2019) -
Risk factors and effective management of preeclampsia
por: English, Fred A, et al.
Publicado: (2015) -
Mechanisms of Endothelial Dysfunction in Pre-eclampsia and Gestational Diabetes Mellitus: Windows Into Future Cardiometabolic Health?
por: McElwain, Colm J., et al.
Publicado: (2020) -
Computational Models on Pathological Redox Signalling Driven by Pregnancy: A Review
por: Manna, Samprikta, et al.
Publicado: (2022)