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Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis

Müller glia (MG) are the principal glial cell type in the vertebrate retina. Recent work has identified the LIM homeodomain factor encoding gene Lhx2 as necessary for both Notch signaling and MG differentiation in late-stage retinal progenitor cells (RPCs). However, the extent to which Lhx2 interact...

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Detalles Bibliográficos
Autores principales: de Melo, Jimmy, Clark, Brian S., Blackshaw, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015061/
https://www.ncbi.nlm.nih.gov/pubmed/27605455
http://dx.doi.org/10.1038/srep32757