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Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insults

In chronic neurodegenerative syndromes, neurons progressively die through a generalized retraction pattern triggering retrograde axonal degeneration toward the cell bodies, which molecular mechanisms remain elusive. Recent observations suggest that direct activation of pro-apoptotic signaling in axo...

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Detalles Bibliográficos
Autores principales: Lassus, Benjamin, Magifico, Sebastien, Pignon, Sandra, Belenguer, Pascale, Miquel, Marie-Christine, Peyrin, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015069/
https://www.ncbi.nlm.nih.gov/pubmed/27604820
http://dx.doi.org/10.1038/srep32777

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