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Simultaneous spatiotemporal mapping of in situ pH and bacterial activity within an intact 3D microcolony structure
Biofilms are comprised of bacterial-clusters (microcolonies) enmeshed in an extracellular matrix. Streptococcus mutans can produce exopolysaccharides (EPS)-matrix and assemble microcolonies with acidic microenvironments that can cause tooth-decay despite the surrounding neutral-pH found in oral cavi...
Autores principales: | Hwang, Geelsu, Liu, Yuan, Kim, Dongyeop, Sun, Victor, Aviles-Reyes, Alejandro, Kajfasz, Jessica K., Lemos, Jose A., Koo, Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015094/ https://www.ncbi.nlm.nih.gov/pubmed/27604325 http://dx.doi.org/10.1038/srep32841 |
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