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Chronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes

BACKGROUND: Angiogenesis is an essential process in endometriosis disease progression. Earlier, we demonstrated that anti-angiogenic peptide, ABT-898 prevents neoangiogenesis of human endometriotic lesions in a xenograft mouse model. Since angiogenesis is essential for normal ovarian and uterine fun...

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Detalles Bibliográficos
Autores principales:	Edwards, Andrew K., Olariu, Irina, Nakamura, Diane S., Ahn, Soo Hyun, Tayade, Chandrakant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015213/ https://www.ncbi.nlm.nih.gov/pubmed/27604347 http://dx.doi.org/10.1186/s12958-016-0192-7

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