Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure

BACKGROUND: Bioavailability of nitric oxide (NO) and hydrogen sulfide (H(2)S) is reduced in heart failure (HF). Recent studies suggest cross‐talk between NO and H(2)S signaling. We previously reported that sodium nitrite (NaNO (2)) ameliorates myocardial ischemia‐reperfusion injury and HF. Nuclear f...

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Detalles Bibliográficos
Autores principales: Donnarumma, Erminia, Bhushan, Shashi, Bradley, Jessica M., Otsuka, Hiroyuki, Donnelly, Erinn L., Lefer, David J., Islam, Kazi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015282/
https://www.ncbi.nlm.nih.gov/pubmed/27473036
http://dx.doi.org/10.1161/JAHA.116.003551

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