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Glibenclamide Is Comparable to Target Temperature Management in Improving Survival and Neurological Outcome After Asphyxial Cardiac Arrest in Rats

BACKGROUND: We previously have shown that glibenclamide (GBC), a sulfonylurea receptor 1–transient receptor potential M4 (SUR1‐TRPM4) channel inhibitor, improves survival and neurological outcome after asphyxial cardiac arrest and cardiopulmonary resuscitation (ACA/CPR). Here, we further compare the...

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Detalles Bibliográficos
Autores principales: Huang, Kaibin, Wang, Ziyue, Gu, Yong, Hu, Yafang, Ji, Zhong, Wang, Shengnan, Lin, Zhenzhou, Li, Xing, Xie, Zuoshan, Pan, Suyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015382/
https://www.ncbi.nlm.nih.gov/pubmed/27413041
http://dx.doi.org/10.1161/JAHA.116.003465