Cargando…

Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

BACKGROUND: Zofenopril, a sulfhydrylated angiotensin‐converting enzyme inhibitor (ACEI), reduces mortality and morbidity in infarcted patients to a greater extent than do other ACEIs. Zofenopril is a unique ACEI that has been shown to increase hydrogen sulfide (H(2)S) bioavailability and nitric oxid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Donnarumma, Erminia, Ali, Murtuza J., Rushing, Amanda M., Scarborough, Amy L., Bradley, Jessica M., Organ, Chelsea L., Islam, Kazi N., Polhemus, David J., Evangelista, Stefano, Cirino, Giuseppe, Jenkins, J. Stephen, Patel, Rajan A. G., Lefer, David J., Goodchild, Traci T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015391/ https://www.ncbi.nlm.nih.gov/pubmed/27381758 http://dx.doi.org/10.1161/JAHA.116.003531

Ejemplares similares

Hydrogen Sulfide Levels and Nuclear Factor-Erythroid 2-Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)
por: Islam, Kazi N, et al.
Publicado: (2015)

Combined Angiotensin Receptor–Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure
por: Trivedi, Rishi K., et al.
Publicado: (2018)

Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure
por: Organ, Chelsea L., et al.
Publicado: (2020)

Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure
por: Li, Zhen, et al.
Publicado: (2018)

Radiofrequency Renal Denervation Protects the Ischemic Heart via Inhibition of GRK2 and Increased Nitric Oxide Signaling
por: Polhemus, David J., et al.
Publicado: (2016)

The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
por: Polhemus, David J., et al.
Publicado: (2014)

Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury
por: Sharp, Thomas E., et al.
Publicado: (2020)

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients
por: Polhemus, David J., et al.
Publicado: (2015)

Novel Göttingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities
por: Sharp, Thomas E., et al.
Publicado: (2021)

Soluble urokinase plasminogen activator receptor: from biomarker to active participant in atherosclerosis and cardiovascular disease
por: Goodchild, Traci T., et al.
Publicado: (2022)

Reply: Tolerating Large Preclinical Models of HFpEF But Without the Intolerance?
por: Sharp, Thomas E., et al.
Publicado: (2021)

Hydrogen Sulfide as a Potential Therapy for Heart Failure—Past, Present, and Future
por: LaPenna, Kyle B., et al.
Publicado: (2021)

Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors
por: Zhao, Yu, et al.
Publicado: (2015)

Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure
por: Donnarumma, Erminia, et al.
Publicado: (2016)

Zofenopril: Blood pressure control and cardio-protection
por: Borghi, Claudio, et al.
Publicado: (2022)

Zofenopril and incidence of cough: a review of published and unpublished data
por: Omboni, Stefano, et al.
Publicado: (2011)

Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2‐Hit” Murine Model
por: LaPenna, Kyle B., et al.
Publicado: (2023)

Serum Metabolomics Reveals Distinct Profiles during Ischemia and Reperfusion in a Porcine Model of Myocardial Ischemia–Reperfusion
por: Goetzman, Eric, et al.
Publicado: (2022)

Correction: Human Cystathionine-β-Synthase Phosphorylation on Serine227 Modulates Hydrogen Sulfide Production in Human Urothelium
por: d’Emmanuele di Villa Bianca, Roberta, et al.
Publicado: (2015)

Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model
por: Kalender, Ali Murat, et al.
Publicado: (2009)

Effects of early treatment with zofenopril in patients with myocardial infarction and metabolic syndrome: the SMILE Study
por: Borghi, Claudio, et al.
Publicado: (2008)

Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available data
por: Borghi, Claudio, et al.
Publicado: (2006)

Hydrogen Sulfide Ameliorates Homocysteine-Induced Cardiac Remodeling and Dysfunction
por: Kar, Sumit, et al.
Publicado: (2019)

Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability?
por: Whiteman, Matthew, et al.
Publicado: (2009)

Formation of Zn- and Fe-sulfides near hydrothermal vents at the Eastern Lau Spreading Center: implications for sulfide bioavailability to chemoautotrophs
por: Hsu-Kim, Heileen, et al.
Publicado: (2008)

Effects of Treatment with Zofenopril in Men and Women with Acute Myocardial Infarction: Gender Analysis of the SMILE Program
por: Franconi, Flavia, et al.
Publicado: (2014)

Insulin-like growth factor 1 reduces coronary atherosclerosis in pigs with familial hypercholesterolemia
por: Sukhanov, Sergiy, et al.
Publicado: (2023)

A crossover randomized comparative study of zofenopril and ramipril on cough reflex and airway inflammation in healthy volunteers
por: Lavorini, Federico, et al.
Publicado: (2014)

Zofenopril versus ramipril in the early phase of acute myocardial infarction with systolic dysfunction: A retrospective study
por: Liu, Xiaoyang, et al.
Publicado: (2020)

Angiotensin System Modulations in Spontaneously Hypertensive Rats and Consequences on Erythrocyte Properties; Action of MLN-4760 and Zofenopril
por: Jasenovec, Tomas, et al.
Publicado: (2021)

Evaluation of pheniramine maleate and zofenopril in reducing renal damage induced by unilateral ureter obstruction. An experimental study
por: Yuvanc, Ercan, et al.
Publicado: (2019)

The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760
por: Cacanyiova, Sona, et al.
Publicado: (2023)

Zofenopril Plus Hydrochlorothiazide and Irbesartan Plus Hydrochlorothiazide in Previously Treated and Uncontrolled Diabetic and Non-diabetic Essential Hypertensive Patients
por: Agabiti-Rosei, Enrico, et al.
Publicado: (2014)

Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy
por: Kar, Sumit, et al.
Publicado: (2019)

H(2)S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins
por: Islam, Rahib K., et al.
Publicado: (2023)

Decreased bioavailability of hydrogen sulfide links vascular endothelium and atrial remodeling in atrial fibrillation
por: Watts, Megan, et al.
Publicado: (2020)

Human Cystathionine-β-Synthase Phosphorylation on Serine227 Modulates Hydrogen Sulfide Production in Human Urothelium
por: d’Emmanuele di Villa Bianca, Roberta, et al.
Publicado: (2015)

Cost-effectiveness of zofenopril in patients with left ventricular systolic dysfunction after acute myocardial infarction: a post hoc analysis of SMILE-4
por: Borghi, Claudio, et al.
Publicado: (2013)

Nitric Oxide Donors in Endotoxic and Septic Shock: Evidence Against Nitric Oxide as a Mediator of Shock
por: Lefer, Allan M.
Publicado: (1998)

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury
por: Xia, Huijing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e1mf8isupv0378dh39g2539gai