Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia‐Inducible Factor 1‐α (HIF1‐α) in an Ovine Model of Acute Myocardial Infarction

BACKGROUND: Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors. Hypoxia‐inducible factor 1‐α (HIF1‐α), rapidly degraded during normoxia, is stabilized during ischemia and upregula...

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Detalles Bibliográficos
Autores principales: Hnatiuk, Anna P., Ong, Sang‐Ging, Olea, Fernanda D., Locatelli, Paola, Riegler, Johannes, Lee, Won Hee, Jen, Cheng Hao, De Lorenzi, Andrea, Giménez, Carlos S., Laguens, Rubén, Wu, Joseph C., Crottogini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015403/
https://www.ncbi.nlm.nih.gov/pubmed/27385426
http://dx.doi.org/10.1161/JAHA.116.003714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015403/
https://www.ncbi.nlm.nih.gov/pubmed/27385426
http://dx.doi.org/10.1161/JAHA.116.003714

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