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Bilateral panuveitis associated with Whipple disease – case report
Purpose: To describe a clinical case and literature review of Whipple disease. Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015619/ https://www.ncbi.nlm.nih.gov/pubmed/27625936 http://dx.doi.org/10.3205/oc000014 |
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author | Lisboa, Maria Domingues, Isabel Pamplona, Jaime Barata, Pedro Morgado, Joana Brotas, Vítor |
author_facet | Lisboa, Maria Domingues, Isabel Pamplona, Jaime Barata, Pedro Morgado, Joana Brotas, Vítor |
author_sort | Lisboa, Maria |
collection | PubMed |
description | Purpose: To describe a clinical case and literature review of Whipple disease. Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical work-up revealed a bilateral panuveitis and an ischemic cerebellar stroke. Result: The diagnosis of Whipple disease was confirmed by histopathological analysis of adenopathy. The patient was treated with cortico-antibiotic therapy with significant clinical improvement. Conclusion: Although rare, Whipple disease is potentially fatal if left untreated, it must be always be taken into consideration before any panuveitis of an unknown cause, even in the absence of gastrointestinal symptoms. |
format | Online Article Text |
id | pubmed-5015619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-50156192016-09-13 Bilateral panuveitis associated with Whipple disease – case report Lisboa, Maria Domingues, Isabel Pamplona, Jaime Barata, Pedro Morgado, Joana Brotas, Vítor GMS Ophthalmol Cases Article Purpose: To describe a clinical case and literature review of Whipple disease. Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical work-up revealed a bilateral panuveitis and an ischemic cerebellar stroke. Result: The diagnosis of Whipple disease was confirmed by histopathological analysis of adenopathy. The patient was treated with cortico-antibiotic therapy with significant clinical improvement. Conclusion: Although rare, Whipple disease is potentially fatal if left untreated, it must be always be taken into consideration before any panuveitis of an unknown cause, even in the absence of gastrointestinal symptoms. German Medical Science GMS Publishing House 2014-01-08 /pmc/articles/PMC5015619/ /pubmed/27625936 http://dx.doi.org/10.3205/oc000014 Text en Copyright © 2014 Lisboa et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License. You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited. |
spellingShingle | Article Lisboa, Maria Domingues, Isabel Pamplona, Jaime Barata, Pedro Morgado, Joana Brotas, Vítor Bilateral panuveitis associated with Whipple disease – case report |
title | Bilateral panuveitis associated with Whipple disease – case report |
title_full | Bilateral panuveitis associated with Whipple disease – case report |
title_fullStr | Bilateral panuveitis associated with Whipple disease – case report |
title_full_unstemmed | Bilateral panuveitis associated with Whipple disease – case report |
title_short | Bilateral panuveitis associated with Whipple disease – case report |
title_sort | bilateral panuveitis associated with whipple disease – case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015619/ https://www.ncbi.nlm.nih.gov/pubmed/27625936 http://dx.doi.org/10.3205/oc000014 |
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