Cargando…

Bilateral panuveitis associated with Whipple disease – case report

Purpose: To describe a clinical case and literature review of Whipple disease. Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical w...

Descripción completa

Detalles Bibliográficos
Autores principales: Lisboa, Maria, Domingues, Isabel, Pamplona, Jaime, Barata, Pedro, Morgado, Joana, Brotas, Vítor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015619/
https://www.ncbi.nlm.nih.gov/pubmed/27625936
http://dx.doi.org/10.3205/oc000014
_version_ 1782452470842130432
author Lisboa, Maria
Domingues, Isabel
Pamplona, Jaime
Barata, Pedro
Morgado, Joana
Brotas, Vítor
author_facet Lisboa, Maria
Domingues, Isabel
Pamplona, Jaime
Barata, Pedro
Morgado, Joana
Brotas, Vítor
author_sort Lisboa, Maria
collection PubMed
description Purpose: To describe a clinical case and literature review of Whipple disease. Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical work-up revealed a bilateral panuveitis and an ischemic cerebellar stroke. Result: The diagnosis of Whipple disease was confirmed by histopathological analysis of adenopathy. The patient was treated with cortico-antibiotic therapy with significant clinical improvement. Conclusion: Although rare, Whipple disease is potentially fatal if left untreated, it must be always be taken into consideration before any panuveitis of an unknown cause, even in the absence of gastrointestinal symptoms.
format Online
Article
Text
id pubmed-5015619
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher German Medical Science GMS Publishing House
record_format MEDLINE/PubMed
spelling pubmed-50156192016-09-13 Bilateral panuveitis associated with Whipple disease – case report Lisboa, Maria Domingues, Isabel Pamplona, Jaime Barata, Pedro Morgado, Joana Brotas, Vítor GMS Ophthalmol Cases Article Purpose: To describe a clinical case and literature review of Whipple disease. Methods: A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical work-up revealed a bilateral panuveitis and an ischemic cerebellar stroke. Result: The diagnosis of Whipple disease was confirmed by histopathological analysis of adenopathy. The patient was treated with cortico-antibiotic therapy with significant clinical improvement. Conclusion: Although rare, Whipple disease is potentially fatal if left untreated, it must be always be taken into consideration before any panuveitis of an unknown cause, even in the absence of gastrointestinal symptoms. German Medical Science GMS Publishing House 2014-01-08 /pmc/articles/PMC5015619/ /pubmed/27625936 http://dx.doi.org/10.3205/oc000014 Text en Copyright © 2014 Lisboa et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License. You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Article
Lisboa, Maria
Domingues, Isabel
Pamplona, Jaime
Barata, Pedro
Morgado, Joana
Brotas, Vítor
Bilateral panuveitis associated with Whipple disease – case report
title Bilateral panuveitis associated with Whipple disease – case report
title_full Bilateral panuveitis associated with Whipple disease – case report
title_fullStr Bilateral panuveitis associated with Whipple disease – case report
title_full_unstemmed Bilateral panuveitis associated with Whipple disease – case report
title_short Bilateral panuveitis associated with Whipple disease – case report
title_sort bilateral panuveitis associated with whipple disease – case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015619/
https://www.ncbi.nlm.nih.gov/pubmed/27625936
http://dx.doi.org/10.3205/oc000014
work_keys_str_mv AT lisboamaria bilateralpanuveitisassociatedwithwhipplediseasecasereport
AT dominguesisabel bilateralpanuveitisassociatedwithwhipplediseasecasereport
AT pamplonajaime bilateralpanuveitisassociatedwithwhipplediseasecasereport
AT baratapedro bilateralpanuveitisassociatedwithwhipplediseasecasereport
AT morgadojoana bilateralpanuveitisassociatedwithwhipplediseasecasereport
AT brotasvitor bilateralpanuveitisassociatedwithwhipplediseasecasereport