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Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease

The mechanisms leading to amyloid-β (Aβ) accumulation in sporadic Alzheimer disease (AD) are unknown but both increased production or impaired clearance likely contribute to aggregation. To understand the potential roles of the extracellular matrix proteoglycan Testican-1 in the pathophysiology of A...

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Detalles Bibliográficos
Autores principales:	Barrera-Ocampo, Alvaro, Arlt, Sönke, Matschke, Jakob, Hartmann, Ursula, Puig, Berta, Ferrer, Isidre, Zürbig, Petra, Glatzel, Markus, Sepulveda-Falla, Diego, Jahn, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015660/ https://www.ncbi.nlm.nih.gov/pubmed/27486134 http://dx.doi.org/10.1093/jnen/nlw065

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