Locally excitable Cdc42 signals steer cells during chemotaxis

Neutrophils and other amoeboid cells chemotax by steering their front towards chemoattractant. While Ras, Rac, Cdc42, and RhoA small GTPases all regulate chemotaxis, it has been unclear how they spatiotemporally control polarization and steering. Using fluorescence biosensors in neutrophil-like PLB-...

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Detalles Bibliográficos
Autores principales: Yang, Hee Won, Collins, Sean, Meyer, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015690/
https://www.ncbi.nlm.nih.gov/pubmed/26689677
http://dx.doi.org/10.1038/ncb3292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015690/
https://www.ncbi.nlm.nih.gov/pubmed/26689677
http://dx.doi.org/10.1038/ncb3292

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