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Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes

We previously reported that overexpression of catalase upregulated xenobiotic- metabolizing enzyme (XME) expression and diminished benzo(a)pyrene (BaP) intermediate accumulation in mouse aortic endothelial cells (MAECs). Endoplasmic reticulum (ER) is the most active organelle involved in BaP metabol...

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Detalles Bibliográficos
Autores principales:	Yang, Fang, Yang, Hong, Ramesh, Aramandla, Goodwin, J. Shawn, Okoro, Emmanuel U., Guo, ZhongMao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015903/ https://www.ncbi.nlm.nih.gov/pubmed/27607467 http://dx.doi.org/10.1371/journal.pone.0162561

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