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Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes
We previously reported that overexpression of catalase upregulated xenobiotic- metabolizing enzyme (XME) expression and diminished benzo(a)pyrene (BaP) intermediate accumulation in mouse aortic endothelial cells (MAECs). Endoplasmic reticulum (ER) is the most active organelle involved in BaP metabol...
Autores principales: | Yang, Fang, Yang, Hong, Ramesh, Aramandla, Goodwin, J. Shawn, Okoro, Emmanuel U., Guo, ZhongMao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015903/ https://www.ncbi.nlm.nih.gov/pubmed/27607467 http://dx.doi.org/10.1371/journal.pone.0162561 |
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