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rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants
The Saccharomyces cerevisiae ribosomal DNA (rDNA) locus is known to exhibit greater instability relative to the rest of the genome. However, wild-type cells preferentially maintain a stable number of rDNA copies, suggesting underlying genetic control of the size of this locus. We performed a screen...
Autores principales: | Kwan, Elizabeth X., Wang, Xiaobin S., Amemiya, Haley M., Brewer, Bonita J., Raghuraman, M. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015940/ https://www.ncbi.nlm.nih.gov/pubmed/27449518 http://dx.doi.org/10.1534/g3.116.030296 |
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