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rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants

The Saccharomyces cerevisiae ribosomal DNA (rDNA) locus is known to exhibit greater instability relative to the rest of the genome. However, wild-type cells preferentially maintain a stable number of rDNA copies, suggesting underlying genetic control of the size of this locus. We performed a screen...

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Detalles Bibliográficos
Autores principales: Kwan, Elizabeth X., Wang, Xiaobin S., Amemiya, Haley M., Brewer, Bonita J., Raghuraman, M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015940/
https://www.ncbi.nlm.nih.gov/pubmed/27449518
http://dx.doi.org/10.1534/g3.116.030296

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