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Suppression of Acid Sphingomyelinase Protects the Retina from Ischemic Injury

PURPOSE: Acid sphingomyelinase (ASMase) catalyzes the hydrolysis of sphingomyelin to ceramide and mediates multiple responses involved in inflammatory and apoptotic signaling. However, the role ASMase plays in ischemic retinal injury has not been investigated. The purpose of this study was to invest...

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Detalles Bibliográficos
Autores principales: Fan, Jie, Wu, Bill X., Crosson, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015980/
https://www.ncbi.nlm.nih.gov/pubmed/27571014
http://dx.doi.org/10.1167/iovs.16-19717