Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects

Elucidating the causes of congenital heart defects is made difficult by the complex morphogenesis of the mammalian heart, which takes place early in development, involves contributions from multiple germ layers, and is controlled by many genes. Here, we use a conditional/invertible genetic strategy...

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Detalles Bibliográficos
Autores principales: Santos, Rosaysela, Kawauchi, Shimako, Jacobs, Russell E., Lopez-Burks, Martha E., Choi, Hojae, Wikenheiser, Jamie, Hallgrimsson, Benedikt, Jamniczky, Heather A., Fraser, Scott E., Lander, Arthur D., Calof, Anne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016002/
https://www.ncbi.nlm.nih.gov/pubmed/27606604
http://dx.doi.org/10.1371/journal.pbio.2000197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016002/
https://www.ncbi.nlm.nih.gov/pubmed/27606604
http://dx.doi.org/10.1371/journal.pbio.2000197

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