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Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy
Radiation therapy (RT) alone has been considered for a long time as the standard therapeutic option for limited stage FL, due to its high efficacy in terms of local disease control with a quite significant proportion of “cured” patients (without further relapses at 10–15 years). Multiple therapeutic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Università Cattolica del Sacro Cuore
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016012/ https://www.ncbi.nlm.nih.gov/pubmed/27648204 http://dx.doi.org/10.4084/MJHID.2016.041 |
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author | Filippi, Andrea Riccardo Ciammella, Patrizia Ricardi, Umberto |
author_facet | Filippi, Andrea Riccardo Ciammella, Patrizia Ricardi, Umberto |
author_sort | Filippi, Andrea Riccardo |
collection | PubMed |
description | Radiation therapy (RT) alone has been considered for a long time as the standard therapeutic option for limited stage FL, due to its high efficacy in terms of local disease control with a quite significant proportion of “cured” patients (without further relapses at 10–15 years). Multiple therapeutic choices are currently accepted for the management of early stage FL at diagnosis, and better staging procedures as well as better systemic therapy partially modified the role of RT in this setting. RT has also changed in terms of prescribed dose as well as treatment volumes. In this review, we present and discuss the current role of RT for limited stage FL in light of the historical data and the modern RT concepts along with the possible combination with systemic therapy. |
format | Online Article Text |
id | pubmed-5016012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Università Cattolica del Sacro Cuore |
record_format | MEDLINE/PubMed |
spelling | pubmed-50160122016-09-19 Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy Filippi, Andrea Riccardo Ciammella, Patrizia Ricardi, Umberto Mediterr J Hematol Infect Dis Review Article Radiation therapy (RT) alone has been considered for a long time as the standard therapeutic option for limited stage FL, due to its high efficacy in terms of local disease control with a quite significant proportion of “cured” patients (without further relapses at 10–15 years). Multiple therapeutic choices are currently accepted for the management of early stage FL at diagnosis, and better staging procedures as well as better systemic therapy partially modified the role of RT in this setting. RT has also changed in terms of prescribed dose as well as treatment volumes. In this review, we present and discuss the current role of RT for limited stage FL in light of the historical data and the modern RT concepts along with the possible combination with systemic therapy. Università Cattolica del Sacro Cuore 2016-09-01 /pmc/articles/PMC5016012/ /pubmed/27648204 http://dx.doi.org/10.4084/MJHID.2016.041 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Filippi, Andrea Riccardo Ciammella, Patrizia Ricardi, Umberto Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy |
title | Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy |
title_full | Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy |
title_fullStr | Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy |
title_full_unstemmed | Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy |
title_short | Limited Stage Follicular Lymphoma: Current Role of Radiation Therapy |
title_sort | limited stage follicular lymphoma: current role of radiation therapy |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016012/ https://www.ncbi.nlm.nih.gov/pubmed/27648204 http://dx.doi.org/10.4084/MJHID.2016.041 |
work_keys_str_mv | AT filippiandreariccardo limitedstagefollicularlymphomacurrentroleofradiationtherapy AT ciammellapatrizia limitedstagefollicularlymphomacurrentroleofradiationtherapy AT ricardiumberto limitedstagefollicularlymphomacurrentroleofradiationtherapy |