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Physical Association of Saccharomyces cerevisiae Polo-like Kinase Cdc5 with Chromosomal Cohesin Facilitates DNA Damage Response

At the onset of anaphase, a protease called separase breaks the link between sister chromatids by cleaving the cohesin subunit Scc1. This irreversible step in the cell cycle is promoted by degradation of the separase inhibitor, securin, and polo-like kinase (Plk) 1-dependent phosphorylation of the S...

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Detalles Bibliográficos
Autores principales:	Pakchuen, Sujiraporn, Ishibashi, Mai, Takakusagi, Emi, Shirahige, Katsuhiko, Sutani, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016123/ https://www.ncbi.nlm.nih.gov/pubmed/27325700 http://dx.doi.org/10.1074/jbc.M116.727438

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