Cargando…
Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4
Skeletal muscle atrophy is a serious and highly prevalent condition that remains poorly understood at the molecular level. Previous work found that skeletal muscle atrophy involves an increase in skeletal muscle Gadd45a expression, which is necessary and sufficient for skeletal muscle fiber atrophy....
Autores principales: | Bullard, Steven A., Seo, Seongjin, Schilling, Birgit, Dyle, Michael C., Dierdorff, Jason M., Ebert, Scott M., DeLau, Austin D., Gibson, Bradford W., Adams, Christopher M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016147/ https://www.ncbi.nlm.nih.gov/pubmed/27358404 http://dx.doi.org/10.1074/jbc.M116.740308 |
Ejemplares similares
-
Get an exact diagnosis in hours
por: Fleming, Nic
Publicado: (2013) -
Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ
por: Ebert, Scott M., et al.
Publicado: (2020) -
Systems-based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle Atrophy
por: Dyle, Michael C., et al.
Publicado: (2014) -
Structural Basis of Host Autophagy-related Protein 8 (ATG8) Binding by the Irish Potato Famine Pathogen Effector Protein PexRD54
por: Maqbool, Abbas, et al.
Publicado: (2016) -
GADD45A is a protective modifier of neurogenic skeletal muscle atrophy
por: Ehmsen, Jeffrey T., et al.
Publicado: (2021)