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β(2)-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function

Bitter taste receptors (TAS2Rs) are G-protein-coupled receptors now recognized to be expressed on extraoral cells, including airway smooth muscle (ASM) where they evoke relaxation. TAS2Rs are difficult to express in heterologous systems, with most receptors being trapped intracellularly. We find, ho...

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Detalles Bibliográficos
Autores principales:	Kim, Donghwa, Pauer, Susan H., Yong, Hwan M., An, Steven S., Liggett, Stephen B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016158/ https://www.ncbi.nlm.nih.gov/pubmed/27342779 http://dx.doi.org/10.1074/jbc.M116.722736

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