Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

Lysosomal acid lipase (LAL) is essential for the clearance of endocytosed cholesteryl ester and triglyceride-rich chylomicron remnants. Humans and mice with defective or absent LAL activity accumulate large amounts of cholesteryl esters and triglycerides in multiple tissues. Although chylomicrons al...

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Detalles Bibliográficos
Autores principales: Grumet, Lukas, Eichmann, Thomas O., Taschler, Ulrike, Zierler, Kathrin A., Leopold, Christina, Moustafa, Tarek, Radovic, Branislav, Romauch, Matthias, Yan, Cong, Du, Hong, Haemmerle, Guenter, Zechner, Rudolf, Fickert, Peter, Kratky, Dagmar, Zimmermann, Robert, Lass, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Lipids
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016185/
https://www.ncbi.nlm.nih.gov/pubmed/27354281
http://dx.doi.org/10.1074/jbc.M116.724054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016185/
https://www.ncbi.nlm.nih.gov/pubmed/27354281
http://dx.doi.org/10.1074/jbc.M116.724054

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