Clathrin Coat Disassembly Illuminates the Mechanisms of Hsp70 Force Generation

Hsp70s use ATP hydrolysis to disrupt protein:protein associations or move macromolecules. One example is Hsc70-mediated disassembly of clathrin coats that form on vesicles during endocytosis. We exploit the exceptional features of these coats to test three models—Brownian ratchet, power-stroke and e...

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Detalles Bibliográficos
Autores principales: Sousa, Rui, Liao, Hsien-Shun, Cuéllar, Jorge, Jin, Suping, Valpuesta, Jose M., Jin, Albert J., Lafer, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016234/
https://www.ncbi.nlm.nih.gov/pubmed/27478930
http://dx.doi.org/10.1038/nsmb.3272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016234/
https://www.ncbi.nlm.nih.gov/pubmed/27478930
http://dx.doi.org/10.1038/nsmb.3272

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