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Clathrin Coat Disassembly Illuminates the Mechanisms of Hsp70 Force Generation
Hsp70s use ATP hydrolysis to disrupt protein:protein associations or move macromolecules. One example is Hsc70-mediated disassembly of clathrin coats that form on vesicles during endocytosis. We exploit the exceptional features of these coats to test three models—Brownian ratchet, power-stroke and e...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016234/ https://www.ncbi.nlm.nih.gov/pubmed/27478930 http://dx.doi.org/10.1038/nsmb.3272 |