A synthetic biology standard for Chinese Hamster Ovary cell genome monitoring and contaminant detection by polymerase chain reaction

BACKGROUND: Chinese Hamster Ovary (CHO) cells are the current industry standard for production of therapeutic monoclonal antibodies at commercial scales. Production optimisation in CHO cells hinges on analytical technologies such as the use of the polymerase chain reaction (PCR) to quantify genetic...

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Detalles Bibliográficos
Autores principales: Templar, Alexander, Marsh, Douglas, Nesbeth, Darren N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016487/
https://www.ncbi.nlm.nih.gov/pubmed/27652083
http://dx.doi.org/10.1186/s40064-016-3074-8

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