LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro

AIMS/HYPOTHESIS: Activation of inflammatory pathways is involved in the pathogenesis of type 2 diabetes mellitus. On the basis of its role in vascular inflammation and in metabolic disorders, we hypothesised that the TNF superfamily (TNFSF) member 14 (LIGHT/TNFSF14) could be involved in the pathogen...

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Detalles Bibliográficos
Autores principales: Halvorsen, Bente, Santilli, Francesca, Scholz, Hanne, Sahraoui, Afaf, Gulseth, Hanne L., Wium, Cecilie, Lattanzio, Stefano, Formoso, Gloria, Di Fulvio, Patrizia, Otterdal, Kari, Retterstøl, Kjetil, Holven, Kirsten B., Gregersen, Ida, Stavik, Benedicte, Bjerkeli, Vigdis, Michelsen, Annika E., Ueland, Thor, Liani, Rossella, Davi, Giovanni, Aukrust, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016561/
https://www.ncbi.nlm.nih.gov/pubmed/27421726
http://dx.doi.org/10.1007/s00125-016-4036-y

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