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Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES

Kunitz-type (KT) protease inhibitors are low molecular weight proteins classically defined as serine protease inhibitors. We identified a novel secreted KT inhibitor associated with the gut and parenchymal tissues of the infective juvenile stage of Fasciola hepatica, a helminth parasite of medical a...

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Detalles Bibliográficos
Autores principales:	Smith, David, Tikhonova, Irina G., Jewhurst, Heather L., Drysdale, Orla C., Dvořák, Jan, Robinson, Mark W., Cwiklinski, Krystyna, Dalton, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016662/ https://www.ncbi.nlm.nih.gov/pubmed/27422822 http://dx.doi.org/10.1074/jbc.M116.724344

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