MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells

The efficiency of pluripotent stem cell differentiation is highly variable, often resulting in heterogeneous populations that contain undifferentiated cells. Here we developed a sensitive, target-specific, and general method for removing undesired cells before transplantation. MicroRNA-302a-5p (miR-...

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Detalles Bibliográficos
Autores principales: Parr, Callum J. C., Katayama, Shota, Miki, Kenji, Kuang, Yi, Yoshida, Yoshinori, Morizane, Asuka, Takahashi, Jun, Yamanaka, Shinya, Saito, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016789/
https://www.ncbi.nlm.nih.gov/pubmed/27608814
http://dx.doi.org/10.1038/srep32532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016789/
https://www.ncbi.nlm.nih.gov/pubmed/27608814
http://dx.doi.org/10.1038/srep32532

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