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Prokineticin 2 antagonist, PKRA7 suppresses arthritis in mice with collagen-induced arthritis
BACKGROUND: Prokineticin 2 (PK2) expression is upregulated in mice with collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis. The purpose of our study was to investigate the effects of PK2 inhibition on CIA. METHODS: PK2, prokineticin receptor (PKR) 1, and PKR2 mRNA transcripts...
Autores principales: | Ito, Haruyasu, Noda, Kentaro, Yoshida, Ken, Otani, Kazuhiro, Yoshiga, Masayuki, Oto, Yohsuke, Saito, Saburo, Kurosaka, Daitaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016855/ https://www.ncbi.nlm.nih.gov/pubmed/27609223 http://dx.doi.org/10.1186/s12891-016-1243-0 |
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