Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia

BACKGROUND: Adipose-derived MSC (AMSCs) possess angiogenic and immunomodulatory properties that may modulate kidney regeneration. Whether these properties are retained in older patients with atherosclerotic vascular disease is poorly understood. Hypoxic conditions are known to modify properties and...

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Detalles Bibliográficos
Autores principales: Saad, Ahmed, Zhu, Xiang-Yang, Herrmann, Sandra, Hickson, LaTonya, Tang, Hui, Dietz, Allan B., van Wijnen, Andre J., Lerman, Lilach, Textor, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016873/
https://www.ncbi.nlm.nih.gov/pubmed/27612459
http://dx.doi.org/10.1186/s13287-016-0389-x

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