Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump

Increased expression of chromosomal genes for resistance-nodulation-cell division-type efflux systems plays a major role in the multidrug resistance of Acinetobacter baumannii. Little is known about the genetic characteristics of clinical strains of Acinetobacter baumannii lacking the AdeABC pump. I...

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Autores principales: López, M., Álvarez-Fraga, L., Gato, E., Blasco, L., Poza, M., Fernández-García, L., Bou, G., Tomás, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017233/
https://www.ncbi.nlm.nih.gov/pubmed/27609928
http://dx.doi.org/10.1128/genomeA.00962-16
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author López, M.
Álvarez-Fraga, L.
Gato, E.
Blasco, L.
Poza, M.
Fernández-García, L.
Bou, G.
Tomás, M.
author_facet López, M.
Álvarez-Fraga, L.
Gato, E.
Blasco, L.
Poza, M.
Fernández-García, L.
Bou, G.
Tomás, M.
author_sort López, M.
collection PubMed
description Increased expression of chromosomal genes for resistance-nodulation-cell division-type efflux systems plays a major role in the multidrug resistance of Acinetobacter baumannii. Little is known about the genetic characteristics of clinical strains of Acinetobacter baumannii lacking the AdeABC pump. In this study, we sequenced the genome of clinical strain Ab421 GEIH-2010 (belonging to clone ST79/PFGE-HUI-1 from the GEIH-REIPI Ab. 2010 project) which lacks this efflux pump.
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spelling pubmed-50172332016-09-20 Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump López, M. Álvarez-Fraga, L. Gato, E. Blasco, L. Poza, M. Fernández-García, L. Bou, G. Tomás, M. Genome Announc Prokaryotes Increased expression of chromosomal genes for resistance-nodulation-cell division-type efflux systems plays a major role in the multidrug resistance of Acinetobacter baumannii. Little is known about the genetic characteristics of clinical strains of Acinetobacter baumannii lacking the AdeABC pump. In this study, we sequenced the genome of clinical strain Ab421 GEIH-2010 (belonging to clone ST79/PFGE-HUI-1 from the GEIH-REIPI Ab. 2010 project) which lacks this efflux pump. American Society for Microbiology 2016-09-08 /pmc/articles/PMC5017233/ /pubmed/27609928 http://dx.doi.org/10.1128/genomeA.00962-16 Text en Copyright © 2016 López et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
López, M.
Álvarez-Fraga, L.
Gato, E.
Blasco, L.
Poza, M.
Fernández-García, L.
Bou, G.
Tomás, M.
Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump
title Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump
title_full Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump
title_fullStr Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump
title_full_unstemmed Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump
title_short Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC (Resistance-Nodulation-Cell Division-Type) Efflux Pump
title_sort genome sequence of a clinical strain of acinetobacter baumannii belonging to the st79/pfge-hui-1 clone lacking the adeabc (resistance-nodulation-cell division-type) efflux pump
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017233/
https://www.ncbi.nlm.nih.gov/pubmed/27609928
http://dx.doi.org/10.1128/genomeA.00962-16
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