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Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation

PURPOSE: The generation of three-dimensional (3D) organoids with optic cup–like structures from pluripotent stem cells has created opportunities for investigating mammalian retinal development in vitro. However, retinal organoids in culture do not completely reflect the developmental state and in vi...

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Detalles Bibliográficos
Autores principales: Chen, Holly Yu, Kaya, Koray Dogan, Dong, Lijin, Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017542/
https://www.ncbi.nlm.nih.gov/pubmed/27667917