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Urethral strictures after radiation therapy for prostate cancer

Urethral stricture after radiation therapy for localized prostate cancer is a delicate problem as the decreased availability of tissue healing and the close relation to the sphincter complicates any surgical approach. We here review the pathophysiology, dosimetry, and the disease specific aspects of...

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Detalles Bibliográficos
Autores principales: Moltzahn, Felix, Dal Pra, Alan, Furrer, Marc, Thalmann, George, Spahn, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017559/
https://www.ncbi.nlm.nih.gov/pubmed/27617311
http://dx.doi.org/10.4111/icu.2016.57.5.309
Descripción
Sumario:Urethral stricture after radiation therapy for localized prostate cancer is a delicate problem as the decreased availability of tissue healing and the close relation to the sphincter complicates any surgical approach. We here review the pathophysiology, dosimetry, and the disease specific aspects of urethral strictures after radiotherapy. Moreover we discuss different treatment option such as direct vision internal urethrotomy as well as techniques for open reconstruction with and without tissue transfer.