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The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia

Precursor-B cell receptor (pre-BCR) signaling represents a crucial checkpoint at the pre-B cell stage. Aberrant pre-BCR signaling is considered as a key factor for B-cell precursor acute lymphoblastic leukemia (BCP-ALL) development. BCP-ALL are believed to be arrested at the pre-BCR checkpoint indep...

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Detalles Bibliográficos
Autores principales:	Chen, Dongfeng, Zheng, Junxiong, Gerasimcik, Natalija, Lagerstedt, Kristina, Sjögren, Helene, Abrahamsson, Jonas, Fogelstrand, Linda, Mårtensson, Inga-Lill
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017602/ https://www.ncbi.nlm.nih.gov/pubmed/27611867 http://dx.doi.org/10.1371/journal.pone.0162638

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