Cell Division Cycle 6 Promotes Mitotic Slippage and Contributes to Drug Resistance in Paclitaxel-Treated Cancer Cells

Paclitaxel (PTX) is an antimitotic drug that possesses potent anticancer activity, but its therapeutic potential in the clinic has been hindered by drug resistance. Here, we report a mechanism by which cancer cells can exit from the PTX-induced mitotic arrest, i.e. mitotic slippage, and avoid subseq...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Yue, Yan, Daoyu, Zheng, Dianpeng, Hu, Zhiming, Li, Hongwei, Li, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017606/
https://www.ncbi.nlm.nih.gov/pubmed/27611665
http://dx.doi.org/10.1371/journal.pone.0162633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017606/
https://www.ncbi.nlm.nih.gov/pubmed/27611665
http://dx.doi.org/10.1371/journal.pone.0162633

Ejemplares similares