Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate

The rapid and strong clinical efficacy of the first-in-class, ingenol mebutate, against actinic keratosis (AK) has resulted in its recent approval. We conducted the first comprehensive analysis of the cellular and molecular mode of action of topical ingenol mebutate 0.05% gel in both AK and uninvolv...

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Detalles Bibliográficos
Autores principales: Emmert, Steffen, Haenssle, Holger A., Zibert, John R., Schön, Margarete, Hald, Andreas, Hansen, Maria H., Litman, Thomas, Schön, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017628/
https://www.ncbi.nlm.nih.gov/pubmed/27612149
http://dx.doi.org/10.1371/journal.pone.0160096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017628/
https://www.ncbi.nlm.nih.gov/pubmed/27612149
http://dx.doi.org/10.1371/journal.pone.0160096

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