Cargando…

Calcineurin Targets Involved in Stress Survival and Fungal Virulence

Calcineurin governs stress survival, sexual differentiation, and virulence of the human fungal pathogen Cryptococcus neoformans. Calcineurin is activated by increased Ca(2+) levels caused by stress, and transduces signals by dephosphorylating protein substrates. Herein, we identified and characteriz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Hee-Soo, Chow, Eve W. L., Fu, Ci, Soderblom, Erik J., Moseley, M. Arthur, Heitman, Joseph, Cardenas, Maria E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017699/ https://www.ncbi.nlm.nih.gov/pubmed/27611567 http://dx.doi.org/10.1371/journal.ppat.1005873

Ejemplares similares

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans
por: Chow, Eve W. L., et al.
Publicado: (2017)

Calcineurin: The Achilles’ heel of fungal pathogens
por: Yadav, Vikas, et al.
Publicado: (2023)

Association of Calcineurin with the COPI Protein Sec28 and the COPII Protein Sec13 Revealed by Quantitative Proteomics
por: Kozubowski, Lukasz, et al.
Publicado: (2011)

Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus
por: Juvvadi, Praveen R., et al.
Publicado: (2015)

Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans
por: Jung, Won-Hee, et al.
Publicado: (2017)

Calcineurin Governs Thermotolerance and Virulence of Cryptococcus gattii
por: Chen, Ying-Lien, et al.
Publicado: (2013)

Phosphorylation of Calcineurin at a Novel Serine-Proline Rich Region Orchestrates Hyphal Growth and Virulence in Aspergillus fumigatus
por: Juvvadi, Praveen R., et al.
Publicado: (2013)

Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides
por: Lee, Soo Chan, et al.
Publicado: (2013)

Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans
por: Son, Ye-Eun, et al.
Publicado: (2018)

Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus
por: Juvvadi, Praveen R., et al.
Publicado: (2015)

Calcineurin Is Required for Pseudohyphal Growth, Virulence, and Drug Resistance in Candida lusitaniae
por: Zhang, Jing, et al.
Publicado: (2012)

Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence
por: Roth, Cullen, et al.
Publicado: (2021)

Calcineurin contributes to RNAi-mediated transgene silencing and small interfering RNA production in the human fungal pathogen Cryptococcus neoformans
por: Yadav, Vikas, et al.
Publicado: (2023)

Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans
por: Son, Ye-Eun, et al.
Publicado: (2019)

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata
por: Chen, Ying-Lien, et al.
Publicado: (2012)

Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans
por: Fu, Ci, et al.
Publicado: (2019)

FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia
por: Ianiri, Giuseppe, et al.
Publicado: (2017)

Comparative analysis of calcineurin signaling between Candida dubliniensis and Candida albicans
por: Zhang, Jing, et al.
Publicado: (2012)

Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs
por: Gobeil, Sophie M.-C., et al.
Publicado: (2021)

Isolation of a fungal calcineurin A mutant suggests that amoebae can counter-select virulence attributes of microbes
por: Idnurm, Alexander
Publicado: (2023)

MoCbp7, a Novel Calcineurin B Subunit-Binding Protein, Is Involved in the Calcium Signaling Pathway and Regulates Fungal Development, Virulence, and ER Homeostasis in Magnaporthe oryzae
por: Wang, Zi-He, et al.
Publicado: (2023)

Erratum for Ianiri et al., “FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia”
por: Ianiri, Giuseppe, et al.
Publicado: (2017)

Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds
por: Wurster, Sebastian, et al.
Publicado: (2020)

Protein Kinase A Regulates Autophagy-Associated Proteins Impacting Growth and Virulence of Aspergillus fumigatus
por: Shwab, E. Keats, et al.
Publicado: (2022)

A Novel Resistance Pathway for Calcineurin Inhibitors in the Human-Pathogenic Mucorales Mucor circinelloides
por: Vellanki, Sandeep, et al.
Publicado: (2020)

Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents
por: Juvvadi, Praveen R., et al.
Publicado: (2019)

Calcineurin-mediated intracellular organelle calcium homeostasis is required for the survival of fungal pathogens upon extracellular calcium stimuli
por: Zhang, Chi, et al.
Publicado: (2021)

The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets
por: Shwab, E. Keats, et al.
Publicado: (2020)

A critical role of calcineurin in stress responses, hyphal formation, and virulence of the pathogenic fungus Trichosporon asahii
por: Matsumoto, Yasuhiko, et al.
Publicado: (2022)

Calcineurin Regulates Conidiation, Chlamydospore Formation and Virulence in Fusarium oxysporum f. sp. lycopersici
por: Hou, Yi-Hsuan, et al.
Publicado: (2020)

Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans
por: Fu, Ci, et al.
Publicado: (2021)

Calcineurin Inhibitors Synergize with Manogepix to Kill Diverse Human Fungal Pathogens
por: Liston, Sean D., et al.
Publicado: (2022)

Quantitative Label-Free Phosphoproteomics Strategy for Multifaceted Experimental Designs
por: Soderblom, Erik J., et al.
Publicado: (2011)

PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex
por: Fu, Ci, et al.
Publicado: (2017)

Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans
por: Desjardins, Christopher A., et al.
Publicado: (2017)

Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom
por: Shertz, Cecelia A, et al.
Publicado: (2010)

Parallels in Intercellular Communication in Oomycete and Fungal Pathogens of Plants and Humans
por: Lee, Soo Chan, et al.
Publicado: (2012)

Calcineurin
por: Creamer, Trevor P.
Publicado: (2020)

Analysis of a Food-Borne Fungal Pathogen Outbreak: Virulence and Genome of a Mucor circinelloides Isolate from Yogurt
por: Lee, Soo Chan, et al.
Publicado: (2014)

Calcineurin in a Crowded World
por: Cook, Erik C., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_63omvctl61lp9t045csssak7qh