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Protein Tyrosine Phosphatase N2 Is a Positive Regulator of Lipopolysaccharide Signaling in Raw264.7 Cell through Derepression of Src Tyrosine Kinase

T cell protein tyrosine phosphatase N2 (PTPN2) is a phosphotyrosine-specific nonreceptor phosphatase and is ubiquitously expressed in tissues. Although PTPN2 functions as an important regulator in different signaling pathways, it is still unclear what is specific target protein of PTPN2 and how is r...

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Detalles Bibliográficos
Autores principales: Ha Thi, Huyen Trang, Choi, Seo-Won, Kim, Young-Mi, Kim, Hye-Youn, Hong, Suntaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017706/
https://www.ncbi.nlm.nih.gov/pubmed/27611995
http://dx.doi.org/10.1371/journal.pone.0162724